ReSyn Biosciences

27/05/2026

is around the corner, and we are very excited to share ReSyn Biosciences conference highlights 🎉!

The impact from our PTM analysis tools continues to expand, please bookmark the presentation by Benton Anderson, M*F am 9:50 titled: "The mouse tissue PTM atlas", with phospho data generated using from !

It is fantastic to see how , the deep plasma profiling workflow for EV enrichment developed in the Michael MacCoss lab, is unlocking valuable biological insights! Please visit poster to learn more about the technology, and example applications in & ...

Vanessa Encinas and Kayla Markuson from the lab of Nicholas M. Riley, PhD are set to reveal some really neat automated glycoproteomics workflows in & !

📢 And finally, we reveal the new tool we have been working on for ... A magnetic bead-based solution for ! Please visit poster to see some early data, scan the poster QR code, and gain early access to collaborate on some amazing applications!

Please visit Previn Naicker, Melissa Vorster, Amy van Graan and Justin Jordaan at to find out more at American Society For Mass Spectrometry (ASMS) in San Diego!

29/04/2026

is around the corner, and momentum is building towards this premier event on the international conference circuit!

Please visit ReSyn Biosciences at , and meet up with Previn Naicker, Melissa Vorster & Amy van Graan to hear about our latest innovations making proteomics sample preparation !

This year we showcase the latest advances in , deep profiling for a range of biofluids using , and our pipeline of NEW innovations in automated & integrated workflows for proteomics…

As always, we have some incredible giveaways championed by our , featuring a few new additions to the 2026 family including , & !

The annual American Society For Mass Spectrometry (ASMS) conference is always an amazing event for , and we can’t wait to catch up with you in !

20/04/2026

📢 Publication Alert🌶️! Researchers from Lunenfeld-Tanenbaum Research Institute, Sinai Health and CiMUS (Center for Research in Molecular Medicine and Chronic Diseases) show that can improve the health of your liver, independent of any weight-loss!

The extended benefits (over an above weight-loss) of semaglutide to the liver has long puzzled scientists, but no longer! improved steatosis, fibrosis, and immune remodeling in a mouse fatty liver disease model, which was attributed to semaglutide-coordinated transcriptional and protein-level reversal of the liver disease.

Thank you also to the authors María Jesús González Rellán and Daniel Drucker for taking the time to interview for the popular science article in Genetic Engineering & Biotechnology News! https://www.genengnews.com/topics/translational-medicine/glp-1-drug-improves-liver-health-independent-of-weight-loss-mouse-study-finds/

Thank you for trusting from ReSyn Biosciences for your liver tissue sample preparation for analysis by ! https://www.cell.com/cell-metabolism/abstract/S1550-4131(26)00105-1

GLP-1 medicines are used to treat people with type 2 diabetes, obesity, and metabolic dysfunction-associated steatohepatitis (MASH). Here, Gonzalez-Rellan et al. demonstrate that semaglutide activates liver signaling networks orchestrated by GLP-1 receptors in liver sinusoidal endothelial cells, pro...

07/04/2026

📢 Publication alert🌶️! Congrats to the team led by the lab of Michael MacCoss, who recently demonstrated the use (with SAX from ReSyn Biosciences) for enrichment of EV's from to study the effects of monoclonal antibody therapy on the fate and function of T-cells in people with type 1 diabetes! https://www.biorxiv.org/content/10.64898/2026.03.27.712461v1

The team used MS based proteomics of enriched serum to analyze longitudinal samples from 20 clinical trial participants to elucidate the effects of and on EV's. Analysis confirmed measurements across multiple draw dates >3300 protein groups, of which 46 protein groups had significant abundance changes after mAb treatment!

The authors conclude: "Taken together, this work demonstrates the utility of the Mag-Net method to evaluate the impacts of therapeutic interventions on serum extracellular vesicles."

30/03/2026

We are pleased to announce Previn Naicker from ReSyn Biosciences will be at in San Diego from 17 to 22 April 2026! Don't miss his presentation on applying for enriching membrane vesicles from spent media for proteomics analysis of the !

10/03/2026

📢Protocol alert🌶️! The Mag-Net workflow using magnetic SAX beads, developed in the lab of Michael MacCoss by Chris Wu, has now been adapted for isolation of extracellular vesicles from mouse and human fluid...

Thank you Tyler Cooper from Université de Montréal (University of Montreal) for making the workflow more accessible by publishing the method paper in the Bio-protocol journal! Enabling researchers to use Mag-Net for isolating EV's from as little as 2 µl of ascites fluid, and for noting that "Mag-Net offers a reproducible, scalable, and automation ready solution for EV isolation from various biofluids." The published protocol is available online: https://bio-protocol.org/en/bpdetail?id=5639&type=0

The protocol was first described in the preprint by Cooper et al in Sep 2025: https://www.biorxiv.org/content/10.1101/2025.09.24.678291v1

09/03/2026

📢 Publication Alert🌶️! Congratulations to Nicole Grinovero, the clinical proteomics laboratory and core facility , and research team at the IRCCS Ospedale Pediatrico Giannina Gaslini for developing a multi-omics workflow (lipidomics and proteomics) from just 10 µL of plasma!

The authors use (developed by the lab of Michael MacCoss with SAX magbeads from ReSyn Biosciences) for the proteomics analysis of EV's in their extremely limited plasma samples from very preterm infants, combined with lipidomics analysis from the very same samples. The approach was used to follow the molecular trajectories of the preterm infants from birth to their term-equivalent age. They note: "Extracting proteins and lipids from the same EV preparation preserves the intrinsic coupling between membrane composition and protein cargo, strengthening cross-layer interpretation", defining the power of multi-omics studies.

The authors suggest: "these findings demonstrate that ultra-low-volume EV multi-omics is not only technically feasible, but capable of resolving structured developmental and injury-related trajectories, providing a scalable framework for longitudinal molecular profiling in neonatal medicine."

love that our products are making a difference in clinical research, and we look forward to the impact this study will have on understanding the disruption of fetal development in very preterm birth.

https://www.medrxiv.org/content/10.64898/2026.02.04.26345553v2

27/01/2026

How time has flown, and it is almost time for the Ubuntu Proteomics Summer School in the beautiful of South Africa, marking the beginning of our conference and travel schedule!

Be sure to catch Previn Naicker partnering with Jesper Velgaard Olsen to teach the latest approaches to ! Please also feel free to connect with during if you would like to discuss more specialized topics, we will be happy to share our in-depth knowledge of sample preparation to advance your proteomics driven research.

Visit the poster presentations by Melissa Vorster and Amy van Graan to hear more about our latest research and development activities related to for deep plasma profiling, and our approach to advance lupus research!

26/01/2026

📢 Publication alerts🌶️! Developed in the lab of Michael MacCoss, using SAX magnetic beads from ReSyn Biosciences, offers a cost-effective method for deep plasma profiling. We are happy to see this workflow becoming clinically relevant, and the momentum it is gaining for identification of new pathways, druggable targets, and quantitive detection of biomarkers from plasma in !

Deanna Plubell and team from the Michael MacCoss lab demonstrate the application of on the for highly multiplex targeted protein assays for clinical application has just been published in MCP! https://www.sciencedirect.com/science/article/pii/S1535947626000010

While in a new bioRxiv & medRxiv preprint, identified 6481 proteins from plasma, providing distinct signatures associated with duration of disease and dopaminergic therapy exposure in . Combined with genome-wide overexpression screens, this provides a resource for biomarker discovery and reveals druggable pathways for precision medicine strategies! https://www.biorxiv.org/content/10.64898/2026.01.19.699565v1

Congrats to all the teams involved, is proud to play a small part in this groundbreaking research!

15/12/2025

📢Publication Alert🌶️! The human cell line phosphoproteome ATLAS has just been released!

The database is a deep empirical resource revealing the kinase activity landscape. Generated by analysing 33 human cell lines the team regroup over 200,000 class I phosphosites. The authors note that this resource is set to accelerate deep and reproducible phosphoproteomics, enable systematic functional mapping of cellular signaling networks, and can empower precision oncology by highlighting actionable kinase targets in diverse cell states.

Congratulations to Claire Koenig, Hayoung Cho, Kristina B. Emdal, Ilaria Piga, Pierre Sabatier, Samuel Lozano Juárez, & Ana Martínez del Val from the lab of Jesper Velgaard Olsen, thank you for making this fantastic resource available!

and courtesy of from ReSyn Biosciences!
https://www.biorxiv.org/content/10.64898/2025.12.05.692571v1